TOPLINE: In a US study of patients without cardiac arrest who required prehospital intubation, rapid sequence intubation (RSI), involving the use of a sedative and paralytic, was associated with increased odds of first-pass success compared with intubation without medication. METHODOLOGY: Researchers performed a retrospective observational analysis using the 2022 Emergency Services Organization Data Collaborative dataset
Actor Shefali Jariwala dies of cardiac arrest at…
TOPLINE: The STOP-or-NOT study of patients undergoing major noncardiac surgery found no difference in the postoperative risk for death or major complications in those who continued or discontinued treatment with renin-angiotensin system inhibitors (RASi) prior to the procedure. A new post hoc analysis of the randomized controlled trial found stratification of preoperative cardiovascular risk does
An approach to treating childhood depression, developed by researchers at WashU Medicine, involves therapists coaching caregivers in helping to build a nurturing and supportive environment for the child. This specialized therapy leads to long-term remission and other benefits, according to a new study. Credit: Sara Moser/WashU Medicine Depression affects 1–2% of children younger than 13
MedPage Today) — Children with infantile-onset Pompe’s disease experienced motor function and cardiac improvements after receiving an adeno-associated virus serotype 9 (AAV9)-mediated gene therapy, a pilot study showed. Among four pediatric…
TOPLINE: A multicenter study found that a 2-hour monitoring period was sufficient for most children who presented to the emergency department with an acute allergic reaction treated with epinephrine. However, children with cardiac involvement needed 4 hours of monitoring, but the risk of repeat dosing beyond this period was low…
Credit: Unsplash/CC0 Public Domain Cannabis use is linked to a doubling in the risk of dying from cardiovascular disease, with significantly heightened risks of having a stroke or acute coronary syndrome—sudden reduced or blocked blood flow to the heart—finds a pooled analysis of real-world data, published online in the journal Heart. The authors of a
TOPLINE: Compared with unvaccinated pregnant women, those who had received an mRNA COVID vaccine in the first trimester did not have a significantly increased risk for major congenital malformations. However, potential links to specific birth defects, such as cardiac anomalies, could not be ruled out. METHODOLOGY: Researchers in Germany conducted a prospective cohort study to
An app that alerts bystanders trained in cardiopulmonary resuscitation (CPR) to a nearby out-of-hospital cardiac arrest can increase survival if volunteer responders arrive before emergency medical services (EMS), according to an Australian study. The analysis of more than 9000 out-of-hospital cardiac arrests in Victoria, published in the Medical Journal of Australia…
Real-world data from two new studies showed no increased risk for cardiac issues in older adults with epilepsy taking the antiseizure medication (ASM) lamotrigine (Lamictal) vs levetiracetam. The findings add to growing evidence that may eventually lead the FDA to reconsider its current cardiac safety warning…