News

05 Jan: ESG Plus Lifestyle Intervention Shows Promise for MASH

TOPLINE: Endoscopic sleeve gastroplasty (ESG) combined with lifestyle changes leads to significant weight loss and improves liver health in patients with metabolic dysfunction–associated steatohepatitis (MASH) and obesity over 72 weeks. METHODOLOGY: A prospective randomized trial was conducted in four centers in Spain from April 2018 to December 2020 to assess the effectiveness and safety of

28 Dec: Cardiac Reoperation Timing Shows No Effect on Mortality

TOPLINE: Compared with later cardiac reoperations, early reoperations demonstrate increased technical complexity with longer operative times and higher requirements for blood transfusion yet show no significant difference in rates of mortality. METHODOLOGY: Researchers conducted this study to explore how the interval between previous cardiac surgeries and subsequent reoperations affects operative mortality and the complexity of

25 Dec: Frailty Risk Increased in Older Adults With Celiac Disease

TOPLINE: Older adults with celiac disease (CeD) face a higher risk of developing frailty within 5 years than those without the condition, a finding that indicates the need for targeted interventions. METHODOLOGY: Researchers used data from Swedish healthcare registries to a conduct nationwide retrospective cohort study that investigated the risk for frailty and its prevalence

Wearable tech takes on heart health: Exploring advancements in cardiovascular disease monitoring

24 Dec: Wearable tech takes on heart health: Exploring advancements in cardiovascular disease monitoring

Overview of different types of HSs measuring devices for the diagnosis of diseases. HS, heart sound. Credit: SmartMat Cardiovascular diseases remain a global health crisis, spurring an urgent demand for innovative diagnostic tools that enable early detection and effective treatment. Wearable heart sound devices represent a significant shift in cardiac care, offering continuous, non-invasive monitoring

Reprogramming cells for heart repair: New method transforms ordinary fibroblasts into mature cardiomyocytes

24 Dec: Reprogramming cells for heart repair: New method transforms ordinary fibroblasts into mature cardiomyocytes

This diagram illustrates how the combination of fibroblast growth factor 4 and ascorbic acid activates the JAK2–STAT3 signaling pathway, promoting the maturation of induced cardiomyocytes (iCMs). This approach effectively reprograms fibroblasts into cardiomyocytes with improved structure and function, offering exciting possibilities for regenerative medicine. Credit: The authors Cardiovascular disease continues to lead as the primary

Salt-seeking behavior traced to specific brain neurons

21 Dec: Salt-seeking behavior traced to specific brain neurons

Credit: Pixabay/CC0 Public Domain Salt, or more precisely the sodium it contains, is very much a “Goldilocks” nutrient. Low sodium levels cause a drop in blood volume, which can have serious, sometimes deadly, health consequences. Conversely, too much salt can lead to high blood pressure and cardiovascular disease. In modern America, where most people consume