Credit: Unsplash/CC0 Public Domain New research from investigators at Mass General Brigham suggests that a commonly used type 2 diabetes medication is linked to a higher rate of heart-related conditions compared to medications that hit other targets. The study examined nationwide data from nearly 50,000 patients treated with different sulfonylureas and found that glipizide—the most
TOPLINE: A tailored exercise adherence intervention integrated into physiotherapy rehabilitation enhanced mobility outcomes in people with vertebral fragility fractures. At 12 months, participants who received adherence support demonstrated better functional mobility and exercise capacity than those who received standard rehabilitation. METHODOLOGY: Researchers conducted a randomised controlled trial to evaluate whether adding a tailored…
MedPage Today) — A multilevel intervention involving parent nudges and clinician reports increased human papillomavirus (HPV) vaccination for most children, though not for some of the most marginalized, a post hoc analysis of a cluster randomized…
Credit: AI-generated image Flinders Health and Medical Research Institute researchers, along with colleagues in the UK and U.S., have linked brighter night-time light exposure to elevated risks of five major cardiovascular diseases. Circadian rhythms govern fluctuations in blood pressure, heart rate, platelet activation, hormone secretion, and glucose metabolism. Long-term disruption of those rhythms in animal
TOPLINE: In a US study of patients without cardiac arrest who required prehospital intubation, rapid sequence intubation (RSI), involving the use of a sedative and paralytic, was associated with increased odds of first-pass success compared with intubation without medication. METHODOLOGY: Researchers performed a retrospective observational analysis using the 2022 Emergency Services Organization Data Collaborative dataset
Actor Shefali Jariwala dies of cardiac arrest at…
An approach to treating childhood depression, developed by researchers at WashU Medicine, involves therapists coaching caregivers in helping to build a nurturing and supportive environment for the child. This specialized therapy leads to long-term remission and other benefits, according to a new study. Credit: Sara Moser/WashU Medicine Depression affects 1–2% of children younger than 13
TOPLINE: The STOP-or-NOT study of patients undergoing major noncardiac surgery found no difference in the postoperative risk for death or major complications in those who continued or discontinued treatment with renin-angiotensin system inhibitors (RASi) prior to the procedure. A new post hoc analysis of the randomized controlled trial found stratification of preoperative cardiovascular risk does
MedPage Today) — Children with infantile-onset Pompe’s disease experienced motor function and cardiac improvements after receiving an adeno-associated virus serotype 9 (AAV9)-mediated gene therapy, a pilot study showed. Among four pediatric…
TOPLINE: A multicenter study found that a 2-hour monitoring period was sufficient for most children who presented to the emergency department with an acute allergic reaction treated with epinephrine. However, children with cardiac involvement needed 4 hours of monitoring, but the risk of repeat dosing beyond this period was low…