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Increased risk factors but not manifestation of disease correlated to placental inflammation

Increased risk factors but not manifestation of disease correlated to placental inflammation

WGCNA of placental villous RNA sequencing data identifies an inflammation-related gene expression module that is highly enriched in Hofbauer cells. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-42300-8 Research led by McGill University, Canada, suggests that disruptions in Hofbauer cell function with preterm birth or intra-amniotic infection may contribute to traits associated with increased risk factors for