There’s still much to learn about how doxorubicin, a 50-year-old chemotherapy drug, causes its most concerning side effects. While responsible for saving many lives, this treatment sometimes causes cardiac damage that stiffens the heart and puts a subset of patients at risk for future heart failure…
MedPage Today) — Unlike a behavioral intervention, nasal sprays were effective in reducing days of illness among high-risk groups vulnerable to respiratory infections, a large randomized controlled trial found. In primary care settings across…
MedPage Today) — Researchers made a case for failure to rescue (FTR) as a potential quality metric in percutaneous coronary intervention (PCI), using records from a large nationwide registry. Although PCI is considered a safe procedure for the…
MedPage Today) — The Mediterranean diet improved cardiometabolic health among kids and teens, a meta-analysis of randomized clinical trials affirmed. Interventions following the diet’s characteristic emphasis on fruit, vegetables, olive oil…
Top line results from a phase 3 trial of vutrisiran (Amvuttra), a new drug from Alnylam for the treatment of transthyretin-mediated amyloidosis with cardiomyopathy, are positive, according to the company. The HELIOS-B study met the primary endpoint, showing a statistically significant reduction, compared with placebo, in the composite of all-cause mortality and recurrent cardiovascular events
Credit: Pixabay/CC0 Public Domain Reducing consumption of processed meat by around one-third could prevent more than 350,000 cases of diabetes in the US over 10 years, a study suggests. Cutting US adults’ processed meat intake by 30%—the equivalent of around 10 slices of bacon a week—would also lead to tens of thousands of fewer cases
Childhood risk factors are associated both directly and indirectly to adult cardiovascular disease (CVD), according to a study published online June 24 in JAMA Network Open. Noora Kartiosuo, from the University of Turku in Finland, and colleagues quantified the direct and indirect effects of childhood risk factors on adult CVD and their relative importance during
SAN DIEGO, California — A review of prescription patterns reveals calcitonin gene-related peptide (CGRP) and gepant medications for migraine reveals significant gender and racial disparities that may affect access to care and health equity. “The study serves as an early steppingstone in identifying opportunities for further research and intervention to expand access to migraine therapeutics,”
Scientists at the Victor Chang Cardiac Research Institute in Australia have produced a first of its kind integrated map of heart cells which unlocks the process of cardiac fibrosis—a major cause of heart failure…
MedPage Today) — As an adjunct to bypass surgery for ischemic cardiomyopathy, a cardiac shockwave therapy aimed at regenerating ischemic myocardium boosted left ventricular ejection fraction (LVEF) and physical function at 1 year in a small sham…