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Reprogramming cells for heart repair: New method transforms ordinary fibroblasts into mature cardiomyocytes

Reprogramming cells for heart repair: New method transforms ordinary fibroblasts into mature cardiomyocytes

This diagram illustrates how the combination of fibroblast growth factor 4 and ascorbic acid activates the JAK2–STAT3 signaling pathway, promoting the maturation of induced cardiomyocytes (iCMs). This approach effectively reprograms fibroblasts into cardiomyocytes with improved structure and function, offering exciting possibilities for regenerative medicine. Credit: The authors Cardiovascular disease continues to lead as the primary

Salt-seeking behavior traced to specific brain neurons

Salt-seeking behavior traced to specific brain neurons

Credit: Pixabay/CC0 Public Domain Salt, or more precisely the sodium it contains, is very much a “Goldilocks” nutrient. Low sodium levels cause a drop in blood volume, which can have serious, sometimes deadly, health consequences. Conversely, too much salt can lead to high blood pressure and cardiovascular disease. In modern America, where most people consume

Clopidogrel Tops Aspirin Post-PCI, Even in High-Risk Cases

TOPLINE: The beneficial effect of clopidogrel monotherapy over aspirin monotherapy in patients who underwent percutaneous coronary intervention (PCI) and remained event free for 6-18 months on dual antiplatelet therapy (DAPT) is consistent, regardless of bleeding risk or PCI complexity, according to a post hoc analysis of the HOST-EXAM trial…

Study links high-fiber diet to delayed progression of blood cancer

Study links high-fiber diet to delayed progression of blood cancer

Credit: Unsplash/CC0 Public Domain Researchers at Memorial Sloan Kettering Cancer Center (MSK) have reported results from the first-ever clinical trial demonstrating that a high-fiber, plant-based dietary intervention may delay progression to multiple myeloma, a rare and incurable blood cancer affecting the bone marrow. The study enrolled 20 participants with a precancerous blood disorder and an