News

Early intervention changes trajectory for depressed preschoolers

Early intervention changes trajectory for depressed preschoolers

An approach to treating childhood depression, developed by researchers at WashU Medicine, involves therapists coaching caregivers in helping to build a nurturing and supportive environment for the child. This specialized therapy leads to long-term remission and other benefits, according to a new study. Credit: Sara Moser/WashU Medicine Depression affects 1–2% of children younger than 13

Cardiovascular Risk Not Key in Presurgical Med Management

TOPLINE: The STOP-or-NOT study of patients undergoing major noncardiac surgery found no difference in the postoperative risk for death or major complications in those who continued or discontinued treatment with renin-angiotensin system inhibitors (RASi) prior to the procedure. A new post hoc analysis of the randomized controlled trial found stratification of preoperative cardiovascular risk does

COVID Shot in the First Trimester Not Tied to Birth Defects

TOPLINE: Compared with unvaccinated pregnant women, those who had received an mRNA COVID vaccine in the first trimester did not have a significantly increased risk for major congenital malformations. However, potential links to specific birth defects, such as cardiac anomalies, could not be ruled out. METHODOLOGY: Researchers in Germany conducted a prospective cohort study to

Early Smartphone-Activated Bystander CPR Can Boost Survival

An app that alerts bystanders trained in cardiopulmonary resuscitation (CPR) to a nearby out-of-hospital cardiac arrest can increase survival if volunteer responders arrive before emergency medical services (EMS), according to an Australian study. The analysis of more than 9000 out-of-hospital cardiac arrests in Victoria, published in the Medical Journal of Australia…

Cardiac Risk Warning for Lamotrigine Challenged

Real-world data from two new studies showed no increased risk for cardiac issues in older adults with epilepsy taking the antiseizure medication (ASM) lamotrigine (Lamictal) vs levetiracetam. The findings add to growing evidence that may eventually lead the FDA to reconsider its current cardiac safety warning…

New Guidelines Shift Diabetes Care Toward Behavior

New guidelines for the management of type 2 diabetes and prediabetes include tools clinicians can use to help patients stick to lifestyle interventions. The guidelines, released on June 10 by the American College of Lifestyle Medicine (ACLM), largely mirror lifestyle guidelines by the American Diabetes Association (ADA) but add specifics about how clinicians can help