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Circadian disruption by night light linked to multiple cardiovascular outcomes

Circadian disruption by night light linked to multiple cardiovascular outcomes

Credit: AI-generated image Flinders Health and Medical Research Institute researchers, along with colleagues in the UK and U.S., have linked brighter night-time light exposure to elevated risks of five major cardiovascular diseases. Circadian rhythms govern fluctuations in blood pressure, heart rate, platelet activation, hormone secretion, and glucose metabolism. Long-term disruption of those rhythms in animal

Rapid Sequence Intubation Boosts First-Pass Success

TOPLINE: In a US study of patients without cardiac arrest who required prehospital intubation, rapid sequence intubation (RSI), involving the use of a sedative and paralytic, was associated with increased odds of first-pass success compared with intubation without medication. METHODOLOGY: Researchers performed a retrospective observational analysis using the 2022 Emergency Services Organization Data Collaborative dataset

Early intervention changes trajectory for depressed preschoolers

Early intervention changes trajectory for depressed preschoolers

An approach to treating childhood depression, developed by researchers at WashU Medicine, involves therapists coaching caregivers in helping to build a nurturing and supportive environment for the child. This specialized therapy leads to long-term remission and other benefits, according to a new study. Credit: Sara Moser/WashU Medicine Depression affects 1–2% of children younger than 13

Cardiovascular Risk Not Key in Presurgical Med Management

TOPLINE: The STOP-or-NOT study of patients undergoing major noncardiac surgery found no difference in the postoperative risk for death or major complications in those who continued or discontinued treatment with renin-angiotensin system inhibitors (RASi) prior to the procedure. A new post hoc analysis of the randomized controlled trial found stratification of preoperative cardiovascular risk does

COVID Shot in the First Trimester Not Tied to Birth Defects

TOPLINE: Compared with unvaccinated pregnant women, those who had received an mRNA COVID vaccine in the first trimester did not have a significantly increased risk for major congenital malformations. However, potential links to specific birth defects, such as cardiac anomalies, could not be ruled out. METHODOLOGY: Researchers in Germany conducted a prospective cohort study to

Early Smartphone-Activated Bystander CPR Can Boost Survival

An app that alerts bystanders trained in cardiopulmonary resuscitation (CPR) to a nearby out-of-hospital cardiac arrest can increase survival if volunteer responders arrive before emergency medical services (EMS), according to an Australian study. The analysis of more than 9000 out-of-hospital cardiac arrests in Victoria, published in the Medical Journal of Australia…