TOPLINE: Compared with unvaccinated pregnant women, those who had received an mRNA COVID vaccine in the first trimester did not have a significantly increased risk for major congenital malformations. However, potential links to specific birth defects, such as cardiac anomalies, could not be ruled out. METHODOLOGY: Researchers in Germany conducted a prospective cohort study to
An app that alerts bystanders trained in cardiopulmonary resuscitation (CPR) to a nearby out-of-hospital cardiac arrest can increase survival if volunteer responders arrive before emergency medical services (EMS), according to an Australian study. The analysis of more than 9000 out-of-hospital cardiac arrests in Victoria, published in the Medical Journal of Australia…
Real-world data from two new studies showed no increased risk for cardiac issues in older adults with epilepsy taking the antiseizure medication (ASM) lamotrigine (Lamictal) vs levetiracetam. The findings add to growing evidence that may eventually lead the FDA to reconsider its current cardiac safety warning…
New guidelines for the management of type 2 diabetes and prediabetes include tools clinicians can use to help patients stick to lifestyle interventions. The guidelines, released on June 10 by the American College of Lifestyle Medicine (ACLM), largely mirror lifestyle guidelines by the American Diabetes Association (ADA) but add specifics about how clinicians can help
Credit: British Heart Foundation A home device that scans someone’s feet as soon as they get out of bed in the morning could keep people with heart failure out of hospital, according to research presented Tuesday at the British Cardiovascular Society conference in Manchester. More than a million people in the U.K. have heart failure
Forest plot showing adjusted hazard ratios for referral to secondary cardiology/cardiac surgery services and aortic valve intervention where the reference group for ethnic groups is the white group, males for females and Index of multiple deprivation (IMD) is level 1 (most affluent group). Credit: British Heart Foundation Women, people from ethnic minority backgrounds, and those
Credit: Antoni Shkraba Studio from Pexels In a new report published in JAMA Cardiology, health policy experts at the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center (BIDMC) have shown that many US adults are unaware they have high blood pressure, diabetes and high cholesterol—three major risk
Credit: Pixabay/CC0 Public Domain Giving a P2Y12 inhibitor anti-clotting drug to patients with coronary artery disease is associated with lower rates of cardiovascular death, heart attack and stroke compared with traditional aspirin, with no increased risk of major bleeding, finds a study published by The BMJ. P2Y12 inhibitors are often given to patients alongside aspirin
MedPage Today) — With 182 trials and 138 novel drugs, the 2025 Alzheimer’s disease drug pipeline has more activity than it did in 2024, an analysis showed. (Alzheimer’s & Dementia: Translational Research & Clinical Interventions) People…
MedPage Today) — CHICAGO — Late-phase trials that showed superiority for an experimental intervention on a surrogate endpoint did not necessarily lead to improvements in overall survival (OS) or quality of life (QOL), according to a meta-epidemiologic…